Lacticaseibacillus paracasei 30 capsules (3 billion CFU/capsule)


The use of Lacticaseibacillus paracasei has been shown to relieve constipation and improve the potentially depressive symptoms in patients with depression1, help prevent cardiometabolic diseases2, alleviate airway allergic inflammation in children3, ameliorate gastrointestinal function in infants and toddlers4, help maintain physical condition in healthy adults6 and moderate symptoms of halitosis10. The use of L. paracasei  had favourable effects in managing constipation in Parkinson’s disease patients5 and provided protective, accelerated recovery and anti-fatigue benefits after muscle damage9. It can also ameliorate hypercholesterolemia and prevent or delay the development of atherosclerosis7. L. paracasei contained in a lotion is safe and effective for treating mild to moderate acne vulgaris8. Overall administration of L. paracasei showed a positive effect on the vaginal microbial ecosystem11. Regular intake of L. paracasei significantly reduces symptoms of moderate to severe dandruff12.


Dosage: 3 billion CFU per capsule

Capsules per order: 30 capsules

Instructions: 1 capsule daily (morning)


  1. Zhang X, Chen S, Zhang M, Ren F, Ren Y, Li Y, Liu N, Zhang Y, Zhang Q, Wang R. Effects of Fermented Milk Containing Lacticaseibacillus paracasei Strain Shirota on Constipation in Patients with Depression: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2021 Jun 29;13(7):2238.
  2. Yang J, Huang J, Huang Z, Xu Y, Li W, Zhu S, Zhao Y, Ye B, Liu L, Zhu J, Xia M, Liu Y. Cardiometabolic benefits of Lacticaseibacillus paracasei 8700:2: A randomized double-blind placebo-controlled trial. Clin Nutr. 2023 Sep;42(9):1637-1646.
  3. Lin EK, Chang WW, Jhong JH, Tsai WH, Chou CH, Wang IJ. Lacticaseibacillus paracasei GM-080 Ameliorates Allergic Airway Inflammation in Children with Allergic Rhinitis: From an Animal Model to a Double-Blind, Randomized, Placebo-Controlled Trial. Cells. 2023 Feb 28;12(5):768.
  4. Ren Z, Zhao A, Zhang J, Yang C, Zhong W, Mao S, Wang S, Yuan Q, Wang P, Zhang Y. Safety and tolerance of Lacticaseibacillus paracasei N1115 in caesarean-born young children: a randomised, placebo-controlled trial. Benef Microbes. 2022 Aug 3;13(3):205-219.
  5. Yang X, He X, Xu S, Zhang Y, Mo C, Lai Y, Song Y, Yan Z, Ai P, Qian Y, Xiao Q. Effect of Lacticaseibacillus paracasei strain Shirota supplementation on clinical responses and gut microbiome in Parkinson’s disease. Food Funct. 2023 Jul 31;14(15):6828-6839.
  6. Sato S, Arai S, Iwabuchi N, Tanaka M, Hase R, Sakane N. Effects of Heat-Killed Lacticaseibacillus paracasei MCC1849 on the Maintenance of Physical Condition in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study. Nutrients. 2023 Aug 4;15(15):3450.
  7. Khongrum J, Yingthongchai P, Boonyapranai K, Wongtanasarasin W, Aobchecy P, Tateing S, Prachansuwan A, Sitdhipol J, Niwasabutra K, Thaveethaptaikul P, Phapugrangkul P, Chonpathompikunlert P. Safety and Effects of Lactobacillus paracasei TISTR 2593 Supplementation on Improving Cholesterol Metabolism and Atherosclerosis-Related Parameters in Subjects with Hypercholesterolemia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2023 Jan 28;15(3):661.
  8. Sathikulpakdee S, Kanokrungsee S, Vitheejongjaroen P, Kamanamool N, Udompataikul M, Taweechotipatr M. Efficacy of probiotic-derived lotion from Lactobacillus paracasei MSMC 39-1 in mild to moderate acne vulgaris, randomized controlled trial. J Cosmet Dermatol. 2022 Oct;21(10):5092-5097.
  9. Lee MC, Ho CS, Hsu YJ, Huang CC. Live and Heat-Killed Probiotic Lactobacillus paracasei PS23 Accelerated the Improvement and Recovery of Strength and Damage Biomarkers after Exercise-Induced Muscle Damage. Nutrients. 2022 Oct 30;14(21):4563.
  10. Wuri G, Liu F, Sun Z, Fang B, Zhao W, Hung WL, Liu WH, Zhang X, Wang R, Wu F, Zhao L, Zhang M. Lactobacillus paracasei ET-22 and derived postbiotics reduce halitosis and modulate oral microbiome dysregulation – a randomized, double-blind placebo-controlled clinical trial. Food Funct. 2023 Aug 14;14(16):7335-7346.
  11. Koirala R, Gargari G, Arioli S, Taverniti V, Fiore W, Grossi E, Anelli GM, Cetin I, Guglielmetti S. Effect of oral consumption of capsules containing Lactobacillus paracasei LPC-S01 on the vaginal microbiota of healthy adult women: a randomized, placebo-controlled, double-blind crossover study. FEMS Microbiol Ecol. 2020 Jun 1;96(6):fiaa084.
  12. Reygagne P, Bastien P, Couavoux MP, Philippe D, Renouf M, Castiel-Higounenc I, Gueniche A. The positive benefit of Lactobacillus paracasei NCC2461 ST11 in healthy volunteers with moderate to severe dandruff. Benef Microbes. 2017 Oct 13;8(5):671-680.